High Throughput Tissue Grinder

High-Throughput Tissue Grinder – QualiGrind™ HT Series

The QualiGrind™ HT Series High-Throughput Tissue Grinder is a bead-beating platform designed for rapid, consistent sample disruption and homogenization in standard tubes and plate formats. It operates through high-frequency vertical oscillation that generates strong shear and impact forces between grinding beads and biological samples, enabling efficient tissue breakdown for downstream applications such as DNA/RNA and protein extraction workflows.

The system offers multiple scalable configurations, supporting both small-batch processing and plate-based high-capacity workflows. A range of adapters, cryogenic accessories, and bead types allows adjustment for different sample hardness levels and temperature sensitivity requirements. Depending on the model, features such as preset programs, touchscreen controls, and integrated safety interlocks help ensure stable and repeatable laboratory operation.

High-Throughput Tissue Grinder – QualiGrind™ HT Series Applications

Tissue and organ homogenization
Processes biological tissues including brain, heart, liver, muscle, bone, and hair, delivering rapid sample disruption for extraction, quantification, and quality control workflows.

Microbial lysis
Facilitates processing of microorganisms such as yeast and E. coli, assisting in effective cell disruption when paired with appropriate bead selection and optimized run settings.

Plant sample grinding
Handles a wide range of plant materials including roots, stems, leaves, flowers, fruits, and seeds, producing consistent homogenates that support reliable extraction performance across multiple batches.

Environmental sample preparation
Prepares soil, sediment, sludge, and similar matrices for analytical procedures where uniform particle distribution and reduced cross-sample contamination are important.

Food, pharmaceutical, polymer, and industrial materials
Suitable for tablets, food matrices, and selected polymers such as PE and PS, supporting controlled particle size reduction for testing, formulation development, and material analysis workflows.

Standards Compliance

• IEC 61010-1
  Defines safety requirements for electrical equipment used in measurement, control, and laboratory environments, ensuring protection of users and safe operating conditions.
• IEC 61326-1
  Specifies electromagnetic compatibility (EMC) requirements, covering both immunity and emission performance for electrical equipment used in measurement, control, and laboratory applications.

High-Throughput Tissue Grinder – QualiGrind™ HT Series Key Features

High-throughput processing capability
Supports rapid, continuous cycle operation for efficient multi-sample tissue grinding and homogenization.

Reduced cross-contamination workflow
Enclosed processing system with independent sample movement helps minimize carryover between samples and maintains workflow cleanliness.

Flexible accessory compatibility
Compatible with a wide range of adapters, tube and plate formats, and optional cryogenic accessories for handling temperature-sensitive materials.

Program-based operation control
Preset programs enable consistent parameter setup, while run data storage (model-dependent) supports traceable and repeatable workflows.

Safety-oriented operation system
Integrated lid-lock protection and emergency braking functions enhance operational safety during use.

Low-noise operational design
Engineered to reduce operational noise levels, helping maintain a more stable laboratory environment during routine processing.

Theory and Method

The QualiGrind™ HT Series operates through high-frequency vertical oscillation, where samples are placed in adapters compatible with standard centrifuge tubes or plate formats. During operation, grinding beads repeatedly collide with the sample, generating strong shear and impact forces that break down tissue structure and cellular components. This controlled mechanical action produces a consistent, uniform homogenate that supports efficient and reliable downstream extraction workflows.

High Throughput Tissue Grinder – QualiGrind™ HT Series Technical Specification

Parameter	QualiGrind™ HT 12	QualiGrind™ HT 24	QualiGrind™ HT 48A	QualiGrind™ HT 60	QualiGrind™ HT 48B
Voltage	220V / 50Hz (110V is also available)
Rated power	100 W	80 W	80 W	180 W	80 W
Time setting	1–9999 s
Speed / Frequency	300–2100 rpm (10–70 Hz)
Data storage	Stores 50 data sets
Clamp stroke / Fixture travel	40 mm (vertical)	34 mm (vertical)
Sample capacity (standard)	2 mL adapter (12-hole)	2 mL adapter (24-hole); 5 mL adapter (12-hole)	2 mL adapter (48-pin); 5 mL adapter (12-pin)	2 mL adapter (60 pins); 5 mL adapter (12 pins)	1–2 mL 48-well (standard config)
Sample capacity (optional)	5 mL adapter (6-hole); 5/10/15/25 mL grinding jars; freezing adapter	5/10/15/25/50/100 mL grinding jars; freezing adapter	5 mL adapter (24-pin); 2 mL adapter (24-pin); 5/10/15/25/50/100 mL grinding jars; freezing adapter	5 mL adapter (24 pins); 2 mL adapter (48 pins); 5/10/15/25/50/100 mL grinding jars; optional cryoadaptor and plate adapters	0.2–0.5 mL 2×96 wells; 5 mL 2×24 wells; 10/15/25/50/100 mL grinding jars; freezing adapter
Grinding method	Wet grinding, dry grinding, pre-freeze grinding
Grinding beads	Std: φ3 mm stainless steel balls (1000 pcs); optional: φ6 mm stainless steel balls (1000 pcs) or zirconia oxide balls
Display	4.3 in TFT touchscreen		7 in TFT touchscreen
Protection	Lid-open protection; emergency stop function
Dimensions (L×W×H)	225×275×390 mm	360×320×500 mm	360×320×500 mm	360×400×520 mm	360×320×550 mm
Weight	≤12 kg	≤29 kg	≤29 kg	≤40 kg	≤35 kg