Advanced Benchtop Freeze Dryer

Advanced Benchtop Freeze Dryer – QualiFD™ B adv Series

The QualiFD™ B adv Series offers an advanced benchtop freeze dryer designed for high-volume daily sample preparation. Compact yet powerful, it integrates automation and protective features to ensure consistent performance during extended operation.

This series comes standard with a high-efficiency vacuum pump, intelligent process control, automatic cold-trap defrost, an oil mist filter, and automated air inlet/drain functions. Its modular design allows flexible configurations tailored to your workflow, including standard tray drying, vial stoppering, or manifold-assisted drying. The touchscreen control system provides real-time process monitoring and keeps detailed records for easy documentation.

Options include electric automatic defrost as standard, with hot-gas defrost available. Built-in safety interlocks and system protection reduce vacuum faults and safeguard the pump and compressor for reliable continuous operation.

Applications of the QualiFD™ B adv Series Benchtop Freeze Dryer

Laboratory Sample Preparation for Biology and Biotech
Ideal for preserving cells, enzymes, and other biological specimens, this benchtop freeze dryer ensures long-term storage while maintaining reconstitution quality. Its tray-based system supports routine drying and handles increased sample throughput efficiently.

Pharmaceutical and Formulation Work
The top-press vial configuration allows vials to be sealed under vacuum after drying, enhancing storage stability and minimizing moisture exposure during handling. This makes it suitable for formulation labs and pharma workflows requiring precise control.

Chemical Synthesis and Temperature-Sensitive Materials
Freeze drying removes solvents without exposing materials to heat, preventing degradation that can occur with conventional drying methods. Modular manifold setups enable drying in bottles or wide-mouth containers according to sample type and format.

Microorganism Preservation in Ampoules
Specialized ampoule interfaces preserve microorganisms such as bacteria and fungi, supporting culture collections, QC labs, and R&D teams that maintain reference strains safely and efficiently.

Standards Compliance for the QualiFD™ B adv Series

• ISO 13408-3 – Provides guidance for aseptic processing in lyophilization to ensure sterile and reliable freeze-drying.
• ASTM E3250 – Defines best practices for freeze dryer instrumentation, focusing on precise temperature and pressure measurements.
• IEC 61010-1 – Specifies safety requirements for laboratory electrical equipment, ensuring safe operation under standard lab conditions.

Advanced Benchtop Freeze Dryer – QualiFD™ B adv Series Key Features

• Automatic Cold-Trap Defrosting – Electric defrost comes standard, with hot-gas defrost available as an option for enhanced flexibility.
• Automated Air Inlet and Drainage – Safety interlocks help prevent vacuum system faults, ensuring reliable operation.
• Oil Mist Filtration – Minimizes pump oil usage and reduces contamination risks in the lab environment.
• Vacuum Pump and Compressor Protection – Cold-trap temperature–linked pump start protection and compressor overload safeguards support continuous use.
• Flexible Vacuum Control – Supports multiple units (Pa, mBar, etc.) with calibration options for time, temperature, and vacuum pressure.
• Maintenance and Alarm Functions – Built-in reminders and alarms help maintain safe, routine operation.
• Optional Modules – Includes eutectic point testing, vacuum adjustment, remote monitoring, scheduled start, and automatic self-check features.
• Customizable Components – Selectable AISI 316L cold-trap material and protective freeze-drying film enhance versatility for specialized workflows.

Freeze Drying Theory and Method – QualiFD™ B adv Series

Freeze drying works by first freezing the sample, then applying a vacuum to enable sublimation, where ice converts directly into vapor without passing through a liquid phase. The vapor is captured in the cold trap, while maintaining a stable vacuum ensures consistent primary drying across cycles.

Secondary drying continues under controlled temperature and vacuum conditions to reduce residual moisture to the desired level. Logged temperature and vacuum trends provide traceable data, supporting repeatability, R&D analysis, and quality control documentation.

Advanced Benchtop Freeze Dryer – QualiFD™ B adv Series Technical Specification

• QualiFD™ B1 adv (Standard) – Features 4–6 stainless steel trays for bulk materials, including liquids, pastes, and solids.
• QualiFD™ B2 adv (Top-Press) – Includes 3 trays with adjustable spacing, designed for vial drying and vacuum stoppering after the drying cycle.
• QualiFD™ B3 adv (Standard + Multiple Manifolds) – Supports tray drying with additional external hanging bottle attachments, suitable for vials or wide-mouth bottles; attachments are removable during operation.
• QualiFD™ B4 adv (Top-Press + Multiple Manifolds) – Combines the top-press vial workflow with manifold functionality for versatile vial and bottle drying.

Specification	QualiFD™ B1 adv	QualiFD™ B2 adv	QualiFD™ B3 adv	QualiFD™ B4 adv
Shelves usable area (m²)	0.12	0.08	>0.12	>0.08
Cold trap temperature (°C)	≤ -60 (no-load); options ≤ -85 and ≤ -110 (no-load)
Vacuum degree (Pa)	≤ 1 (no-load)
Ice capacity (kg/24 h)	3–4
Material tray (mm)	φ200	φ180	φ200	φ180
Layers of tray (pcs)	4	3	4	3
Tray spacing (mm)	70
Power at -60 °C (W)	970
Weight at -60 °C (kg)	41	62	41	62
Overall dimensions at -60 °C (mm)	610 × 430 × 360
Drying chamber (mm)	φ260 × 430
Cold trap diameter (mm)	φ215 × 145
Vial capacity (φ12 mm)	—	492	—	492
Vial capacity (φ16 mm)	—	297	—	297
Vial capacity (φ22 mm)	—	147	—	147
Defrosting	Electric defrosting
Voltage	1Ph + N + PE, 220V (110V is also available)